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Sulforaphane inhibits the growth of KPL-1 human breast cancer cells in vitro and suppresses the growth and metastasis of orthotopically transplanted KPL-1 cells in female athymic mice

These proteins, via interactions with their preferred extracellular matrix (ECM), promote cell adhesion while also serving as mechanosensors (reviewed in Saegusa et al., 2009)

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The regulatory role of the N-terminal region of CGS has also been described upon induction of folate deficiency in Arabidopsis (Loizeau et al., 2007)