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Endocannabinoids, anandamide and 2-AG, regulate mechanosensitivity of mucosal afferents in the Guinea pig bladder

While smoking prevalence has generally decreased over recent decades [3], smoking rates among young adults remain high, and evidence suggests many people who smoke initiate smoking in young adulthood, making this demographic an important group for new smoking cessation interventions [4,5,6,7,8,9]

It is especially prevalent among Cockneys in England, and was first used in the early 19th century in the East End of London

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It also fits Mercury Grand Marquis, Mountaineer