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Some of the complications associated with Crohns disease include fistulas (unwanted connections between two body parts), severe bleeding, intestinal blocking, and life-threatening side effects from medications

While this is a small percentage of the population, it still translates into millions of customers just in the United States

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However, a recent post-hoc analysis of trials of tofacitinib in patients with UC found there was no significant difference in the rates of deep vein thrombosis or pulmonary embolism in patients treated with tofacitinib compared to those on no treatment [33]

Nevertheless, several authorities have now chosen to issue warnings