But, whichever of these monikers one chooses, they all describe the same method of enjoying a smoke: electrically heating tobacco to just below combustion point and inhaling the practically odorless vapor
This not only interferes with vascular homeostatic signaling chemically (via production of free radicals), but also physically through separation of the endothelium from smooth muscle cells, and, at later stages, by disrupting the endothelial cell monolayer [25, 52]
This builds the necessary muscle memory and prevents accidental inhalation
Given that the average usage time is 30 minutes, we can assume that less nicotine will be released in that time meaning that the nicotine uptake from such a pouch will be somewhat lower
This may give clues for further examination, e.g