Drug repurposing: sulfasalazine sensitizes gliomas to gamma knife radiosurgery by blocking cystine uptake through system Xc-, leading to glutathione depletion
doi: 10.3389/fbioe.2023.1161472 Received 08 February 2023 Accepted 24 February 2023 Published 10 March 2023 Volume 11 - 2023 Edited by Wen Sun, Dalian University of Technology, China Reviewed by Xin Liu, The University of Chicago, United States Xiaobo Wang, Fourth Military Medical University, China Updates Copyright 2023 Liu, Hao, Liu and Hu
However, several users report taking this product on an empty stomach with vitamin C to help improve absorption, a strategy with some biochemical rationale given vitamin Cs role in glutathione recycling
NAC 1000 mg is especially beneficial for active people, older adults, and people who live or work in polluted environments
Selenium: This mineral is a co-factor for the enzymes that allow glutathione to neutralize free radicals