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Among the four cell/ in vitro and animal studies 18,26,27,31 , all showed that acute exposure to e-cigarettes promoted the growth of different cancers such as bladder cancer 27 , oral squamous cell carcinoma 18,31 , and brain tumor 26

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Indeed, the PV-loop curve revealed a shift towards higher volumes for mice exposed to ECA 30 W and to CS-exposed mice although at a lower intensity but not with 18 W ECA-exposed mice

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