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In adults, tobacco smoking can severely impair hippocampus-dependent functions, such as spatial navigation and new memory formation, assessed by Morris Water Maze in animal models (Bannerman et al., 2014

One prominent theme used in tobacco advertising is that smoking can help solve some personal and emotional problems by relieving stress and promoting relaxation. Many e-cigarette brands are now tapping into themes of stress relief and mental wellbeing as well

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Harris, a non-smoker, lived to be 90

17 However, subsequent meta-analyses have not established a causal link, with rates of reported serious adverse effects in RCTs being similar between varenicline, NRT and placebo