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This is similar to what happens with caffeine, which is why both habits are commonly linked to increased sweating

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Compromised blood supply : Smoking reduces blood supply to the healing nasal framework, increasing chances of tissue death and collapse of nostrils/bridge

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Other factors that can lead to smokers lines are: Genetics Repeated facial expressions, like pouting and smiling Drinking from a straw/bottle Dental problems Playing musical instruments, like the harmonica and flute Chronic dryness of the lips and skin around the mouth Best treatments for smokers lines The best treatment for smokers lines depends on your lip and skin condition and your desired results