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I quickly snuffed out the cigarette as the conductor walked down the aisle, looking everyone over

Notably, subsequent studies demonstrated the relevance and significance of gene expression changes in minimally invasive sites (e.g., mainstem bronchus) within the airway field of injury to early detection of lung cancer in smokers with suspicion of the disease (26, 27, 30, 31)

It applies to any instance where a drivers mental or physical abilities are impaired by a substance to a degree that jeopardizes their safety as well as that of others