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Data showed that WT-Bcr-Abl-32D cells had very low levels of dNTPs as compared to those in T315I-Bcr-Abl-32D and untransformed 32D cells, with the most significant difference in dTTP pool (Fig

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Propionyl-CoA carboxylase has a domain, called the biotin transfer (BT) domain, that is not found in the other biotin-dependent carboxylase family enzymes

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The study thereby illuminates the intricate interplay between SFNs diverse biochemical effects and its ability to modulate HDAC activity, ultimately elucidating the multifaceted molecular underpinnings of their synergistic anticancer effects [42]