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Moreover, components of retrograde menstruation, including heme, iron ions and apoptotic endometrial cells, are known to induce oxidative stress, intensifying the inflammatory response (15)

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Dexamethasone reduces acute tubular necrosis without improving renal failure To understand how these opposing mechanisms affect ferroptosis in complex pathophysiological settings, we next focused on acute kidney injury (AKI), which has been established as a standard model for ferroptotic cell death in vivo [9]

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