Nonalcoholic steatohepatitis is associated with altered hepatic microRNA expression
The high-affinity binding sites on albumin allow for non-covalent drug binding, particularly at Sudlows site I and II, which enable the transport of hydrophobic drugs such as paclitaxel, doxorubicin, and methotrexate [106]
The pK a , solubility, and lipophilicity are among the most fundamental physicochemical properties of a drug candidate, and their measurements are essential for both in silico and in vitro evaluation of drug-like properties
Buneeva, O., & Medvedev, A
After the big three, the distribution flattens quickly, with Ohio, New York, Washington, and Illinois forming a second tier in the high twenties to low thirties