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Metals such as arsenic, beryllium, cobalt, chromium, cadmium, lead and nickel are radioactive substances and oxidizing chemicals can harm the smokers heart, blood vessels, and muscles when interacting with cholesterols, coating the arterial walls with fatty deposits leading to heart attacks and brain stroke

Science 231 , 497499 (1986)

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However, if the immune system is compromised, Candida albicans can overgrow on mucous membranes or moist skin, particularly following chemotherapy, leukaemia or an HIV infection/AIDS