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Early, frequent cannabis users had a 51% higher chance of seeking care for mental health problems in young adulthood compared to those who didn't use the drug

Self-reported smoking status is considered valid, especially for those aged 20 and above [38], so it is unlikely that misclassification by smoking status significantly affected our results

However, the multipronged approach is more difficult to tackle

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[150] TSNAs N -nitrosonornicotine (NNN), 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), N-nitrosoanabasine, and nitrosoanatabine were detected in five e-liquid samples from two companies at levels comparable to other nicotine replacement products