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In a 6-month clinical study in the USA, smokers who switched from smoking cigarettes to predominant THS use showed significant improvements in clinical risk endpoints associated with O 2 delivery (decreased carboxyhaemoglobin levels), inflammation (reduced white blood cell count), and COPD (increased FEV 1 ), although their plasma nicotine levels remained similar to that in smokers
Khan MMA, Rahman MM, Jeamin SS, Mustagir MG, Haque MR, Kaikobad MS
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In addition, manufacturers should ensure that packaging and marketing emphasize that reduced-risk products offer an equivalent or better experience to traditional products with lower health risks to further encourage behavioral change
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