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A 2015 report from the National Survey on Drug Use and Health showed that LGB adults were more than twice as likely to abuse substances as their straight peers, and are up to four times as likely to use crystal meth, due in part to the minority stress they experience from bullying and discrimination

However, the epidemiological evidence from population-based studies is mixed

And unfortunately vaping has become rampant among teens and young adults

These channels are responsible for regulating agonist affinity, ion selectivity, desensitization, and downstream signaling 2

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