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10.1371/journal.pmed.1004200 65 LoprestiA

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Mathur P.P., Chattopadhyay S

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Overcoming opioid addiction is possible and often requires professional help and support

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We also confirmed the delayed formation of the thiomethyl metabolites compared to conventional APAP metabolites, likely related to delayed reabsorption into the systemic circulation after the enterohepatic circulation

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Injection delivers drug to systemic circulation more reliably, which matters for musculoskeletal targets

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