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Mitochondrial dysfunction with loss of cytochrome c and changes in cellular redox status has been shown to alter TGF- signaling in fibroblasts, promoting fibrogenesis, and mitochondrial ROS can directly stimulate alveolar epithelial cell changes towards a profibrotic phenotype (Henderson and OReilly, 2021
The left stamp in this illustration was part of the series of 1898, and the right stamp is one of the John Quincy Adams type that was run in a series beginning with 110 in 1940 and continuing through 125 in 1955, with several values being used into 1958
