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E-cigarette use has skyrocketed In the United States, cardiovascular disease is responsible for about one-third of smoking-associated deaths in smokers, and secondhand smoke causes approximately 34,000 early deaths from heart disease each year in nonsmokers

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Epidemiology of tobacco use and male infertility Numerous risk factors have been proposed for male infertility including erectile dysfunction, varicocele, congenital dysplasia, endocrine disorders, immune factors, sexually transmitted infections, and exposure to chemicals and radiation (Krausz, 2011)

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