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Specifically, the FDA requests comments, including supporting data and research, regarding whether and to what extent this proposed rule would result in an increase in illicit trade in [normal nicotine content] cigarettes and certain other combusted tobacco products covered by the proposed nicotine product standard and how any such increase could impact public health

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Avoid Irritants: Avoid other irritants, such as cigarette smoke, strong odors, and pollution, which can exacerbate a sore throat 4

FASEB J 27:965977 Cavalcante AG, de Bruin PF (2009) The role of oxidative stress in COPD: current concepts and perspectives