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That would subject them to the same taxes and regulations as the broader cigarette industry, which the newspaper said would be likely to put them out of business

Both outcomes were associated with a one-star rating, thus indicating weak evidence of an association

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We think the Rhus glabra may have been mixed with tobacco for its medicinal qualities and to improve the flavor of smoke. The discovery was made possible by a new metabolomics-based analysis method that can detect thousands of plant compounds or metabolites in residue collected from pipes, bowls and other archeological artifacts

[26] This transitioned the colony to a cash-crop focused one, monocropping tobacco by 1613, the year the first shipment (of 4 barrels) arrived in London