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The majority of clinical evidence derives from substitutes for the oral cavity [109, 110, 114117, 122, 127, 128, 130, 134, 136, 139]

General tissue maintenance: Particularly relevant as people age past 40 when natural GHK-Cu levels drop significantly

Their conclusion: sleep improvement under DSIP treatment is of little clinical significance. [11] Bes and colleagues in Amsterdam ran a double-blind matched-pairs parallel-groups design in 16 chronic insomniacs and found the statistically significant effects were weak and in part could be due to an incidental change in the placebo group, with subjective sleep quality unchanged

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