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In fact, tobacco smoke, which contains more than 7000 chemical compounds, affects bone mineral density (BMD) both directly and indirectly, as it has an impact on the RANK-RANKL-OPG pathway, intestinal microbiota composition, and calciumphosphate balance

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The intriguing Tobacco Leaves, Spices, and Incense top notes create an inviting smoky aroma

World Health Organization: WHO Framework Convention on Tobacco Control (FCTC)