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Importance of Diagnostic Testing: While no direct test exists for smoking's mental health impact, screenings for anxiety and depression are important

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In line with this finding, a preclinical study showed that there is a sexually dimorphic effect of estradiol on the D 2 R, where estradiol rapidly downregulates D 2 binding in females but not in males (Bazzett and Becker, Among women, we also observed a trend such that lower levels of free testosterone were associated with lower dlPFC D 2 R availability pre-amphetamine compared to post-amphetamine, consistent with our hypothesis

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Considering these factors, more evidence is needed to understand how e-cigarette use can aid smoking cessation