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Daily running distances increased by approximately 150% in exercised mice receiving 5-Amino-1MQ treatment, compared to 75% increase in exercise-only groups, with the treatment group maintaining elevated performance more consistently over the 8-week study period

As Imperial College Londons Ivan Koychev noted: People exposed to GLP-1RAs over many years appear to have a lower risk of ever developing dementia, which suggests an influence on the earliest pathogenic processes rather than on established neurodegeneration. 2

10.1016/0304-3940(93)90669-C 9 LiX.OrwarO.RevesjC.SandbergM

Biochemistry 38(42):1378713794 Dekker LV, Parker PJ (1997) Regulated binding of the protein kinase C substrate GAP-43 to the V0/C2 region of protein kinase C-delta

The most commonly reported side effect in human observational data is a mild, transient irritation of the nasal mucosa