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This system releases a neurotransmitter called acetylcysteine which binds to muscarinic receptors that are randomly scattered along the bronchial smooth muscle

Although OM is a multifactorial disease involving Eustachian tube (ET) dysfunction, allergy, upper respiratory infection, and various environmental factors, the primary cause is bacterial infection of the middle ear (ME) mainly by Streptococcus pneumoniae , non-typeable Haemophilus influenzae (NTHi), or Moraxella catarrhalis 4

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These studies consistently show that long-term exposure to higher PM2.5 concentrations is significantly associated with lung cancer mortality in a dose-dependent manner and with significant regional differences

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