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During the 1990s, more than 40 states filed suit against major tobacco companies for several forms of misconduct, some involving speech regarding the health risks of their product

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Another might cite disease as the overriding problem, while others take issue with the inflated medical costs related to smoking

In total, over 665,000 genotyped single nucleotide polymorphisms (SNPs) 22,24 and over 15,000,000 imputed SNPs were available for analyses