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Attenuating astrocyte activation accelerates plaque pathogenesis in APP/PS1 mice

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The BBB, composed of tightly joined endothelial cells, astrocytic end-feet, and pericytes, serves as a selective barrier that regulates the passage of substances from the bloodstream into the brain parenchyma (Oldendorf, 1971), while macromolecules such as transferrin and insulin use endothelial receptor-mediated transport (Nance et al., 2022)

Montes-Rocha JA, Alonso-Castro AJ, Carranza-lvarez C (2024) Mechanism of heavy metal-induced stress and tolerance

The necessity of the simple tests for diabetic peripheral neuropathy in type 2 diabetes mellitus patients without neuropathic symptoms in clinical practice