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The nicotine in tobacco is a highly addictive substance, and this is what keeps people coming back to cigarettes, so it was essential that the liquid used for vaping - known as e-liquid or vape juice' - contained nicotine so that it could be used as an effective substitute for tobacco

To determine toxic doses of E-liquid, A549 cells were treated with 2 mL of the following concentrations of E-liquid minus nicotine: 0, 0.22, 2.2, 11, 22 & 44 mM (0, 0.1, 1, 5, 10 & 20%, respectively)

From fruity to minty, the possibilities are endless

Youth use of e-cigarettes is concerning because of the potential for nicotine addiction, the harms of nicotine use on adolescent brain development, the harms of other substances contained in the inhaled e-cigarette aerosol, and the link between e-cigarette use and subsequent use of more harmful tobacco products

When they're all working together, you get a more nuanced, potentially more therapeutic experience