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By then, they were owned by Imperial Tobacco, and though the brands still exist, the market share of dark leaf tobacco, with its stronger taste and higher nicotine content, has plummeted

Regulation Data cross-referenced where possible using the following sources :1

What we do know from recent epidemiological evidence from the USA is that those who both vape and smoke are at an additional four-fold increased risk of developing lung cancer, said co-author Freddy Sitas, an epidemiologist at UNSW

While e-cigarettes generally contain fewer harmful substances than traditional cigarettes, the aerosol produced by e-cigarettes still contains several different harmful or potentially harmful substances, including: 7 Nicotine Ultrafine particles Diacetyl Volatile organic compounds Carcinogens Heavy metals such as nickel, tin, and lead Who Uses E-Cigarettes

The upper and lower bounds for smokers and non-smokers correspond to the 95% uncertainty interval (UI) of the death estimates in the GBD data