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Characterising Spree Bar: an examination of the popularity, marketing and composition of a vaping device with a nicotine analogue across multiple data streams Richard J OConnor, Dongmei Li, Zidian Xie, Michelle K Page, Nicholas J Felicione, Liane M Schneller-Najm, Puhua Ye, Alivia Raczyk, Maansi Bansal-Travers, Maciej Lukasz Goniewicz Tobacco Control 12

Additional experimental and clinical studies will lead to a better understanding of the underlying molecular mechanisms of the regulation of endothelial function in response to single, short-term, and long-term exposure to cigarette smoke and next-generation tobacco and nicotine products