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As such, one plausible mechanistic account is that repeated stimulation of high densities of nAChRs by nicotine may contribute to neurotoxicity within discrete regions and/or increase the vulnerability of those regions to other volatile compounds in tobacco smoke [19] which ultimately manifest as gray matter decreases

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Key Concepts and Summary In the market for goods and services, quantity supplied and quantity demanded are often relatively slow to react to changes in price in the short run, but react more substantially in the long run

This means that the heart has to work harder to supply the body with the oxygen it needs, leading to an increased risk of heart disease and heart failure