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Food and Drug Administration (FDA) Commissioner and the Center for Tobacco Products (CTP) Director stated in 2017, Nicotine, though not benign, is not directly responsible for the tobacco-caused cancer, lung disease, and heart disease that kill hundreds of thousands of Americans each year

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However, lung tissues do not grow back, unlike other parts of the body

Like any nicotine product, the pouches can have short-term side effects such as elevated heart rate, irritation and nausea

However, there is little scientific evidence supporting the effectiveness of detox drinks or detox kits, and their results can be unreliable