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Recently, a growing number of researches have been performed on the MPs presence in different environmental samples, including coastline sediment 12,13 , urban runoff 14,15 , organic solid waste 16,17 , landfill leachate 18,19 , indoor dust 20,21,22,23 , air 24,25 , and ballast water 26,27

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In parallel, nicotine-related alterations in GABA signaling observed ex vivo were associated with enhanced diazepam-induced inhibition of lateral VTA DA neurons in vivo