By targeting the cell cycle inhibitors Cdkn1a and Ccng2 , miR-302b can release cell cycle arrest, restore the proliferation ability of senescent cells, and significantly reverse the aging phenotype of mice
References 1 DobricADe LucaSNSpencerSJBozinovskiSSalingMMMcDonaldCFet al
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However, the conflicting findings of expression patterns may not adequately illustrate a functional consequence of the role of CD36
In a recent study on active forgetting of cold shock-sensitive or anesthesia-sensitive memory (ASM) and cold shock-insensitive or anesthesia-resistant memory (ARM) in Drosophila , it was found that the Arp2/3 complex was only required for Cdc42/WASP mediated ARM forgetting but not for Rac1/WAVE mediated ASM forgetting, and instead, Rac1/WAVE might function through another protein called Dia ( FIGURE 3 Rho GTPases in Memory Ample studies have indicated that Rho GTPases are involved in learning and memory
