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In humans theres essentially no data on half-life, mechanism, or long-term side effects (source)

Naidoo J, Wang X, Woo KM, Iyriboz T, Halpenny D, Cunningham J, et al

Energy and recovery: Community reports describe more consistent daytime energy and reduced post-exercise fatigue by week 3-4, particularly in users with high baseline oxidative stress (smokers, heavy exercisers, those with chronic inflammation)

Interestingly, omega-3 PUFAs were evaluated in rat models of intestinal damage by MTX, and this study demonstrated that omega-3 PUFAs exhibited the ability to prevent intestinal damage and stimulate intestinal recovery

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