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A reduction in size, number and function of mitochondria is associated with aging, and supporting mitochondria with essential nutrients like B12 and NAD can potentially slow and even reverse the aging process

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Those most at risk include vegans and vegetarians, people with digestive conditions such as Crohn's disease, coeliac disease or IBS, those taking long-term metformin or proton pump inhibitors, older adults whose ability to absorb B12 through the gut declines naturally with age, those with pernicious anaemia, and anyone with a history of chronic alcohol use

(PubMed) Shen L, Ji HF

Additionally, B12 is involved in energy metabolism, aiding in the conversion of food into energy, and has implications for mood regulation through its role in neurotransmitter synthesis