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doi: 10.1079/BJN20061855 156

The multifaceted mechanism of action of 5FU involves direct incorporation of its metabolites into DNA (FdUTP) and RNA (FUTP), as well as inhibition of thymidylate synthase (TS) via FdUMP 4,5 , making it more difficult to identify rational combination partners that would enhance clinical responses without eliciting adverse systemic toxicity

doi: 10.1001/jamaoncol.2015.1377 140 MiyakawaY.OtsukaM.ShibataC.SeimiyaT.YamamotoK.IshibashiR.et al

Cross-linked membranes were incubated with 0.02% methylene blue to validate uniform DNA loading

Hair Loss: A high dosage of glutathione can cause hair fall