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Protocols using doses below 0.5mg daily may require 1620 weeks to demonstrate observable improvement

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These may include: Irritation, redness, or slight swelling at the injection site Mild headaches Nausea Temporary discomfort Serious side effects are rare, but long-term safety data is still emerging

Key points Increased intestinal permeability occurs in a wide range of disorders, including inflammatory bowel disease, coeliac disease and graft-versus-host disease, but the relative contributions of barrier dysfunction and immune responses are unclear