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Manganese-based functional nanoplatforms: Nanosynthetic construction, physiochemical property, and theranostic applicability

For example, GA has been shown to bind and stabilize G-quadruplex DNA structures in oncogene promoters (such as c-Myc), leading to transcriptional downregulation of those genes (155)

10.1126/science.1151526 175 YuD.ZhaoY.WangH.KongD.JinW.HuY.et al (2021)

In humans, even a single hour of challenging exercise induces significant ROS emission, oxidative damage, and mitochondrial impairments [209], including variable numbers of swollen mitochondria [210]