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Exercise optimization during combination therapy The right exercise approach amplifies the effects of both compounds while protecting lean mass

It is essential for the proper functioning and growth within the organism

To evaluate the impact of the inter-individual variability (IIV) in the predicted PK and in the PK/PD time course, three levels of IIV were considered (with 15%, 30%, and 45% coefficient of variation [CV])

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The trial followed 731 adults with heart failure with preserved ejection fraction (HFpEF) and obesity who received either tirzepatide or a placebo over the course of a year