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Since Ozempic came to market in 2017 to treat type 2 diabetes, drugmakers Eli Lilly and Novo Nordisk A/S have been competing to develop next-generation diabetes and weight loss drugs

While some changes may be innocuous, others, such as turning the active ingredient in a tablet into an untested nasal spray, could pose greater risks

This impairment of DNA synthesis affects the rapidly dividing cells of the bone marrow earlier than other cells, resulting in the production of large, immature, hemoglobin-poor red blood cells (macrocytosis), as well as effects on white blood cells, including abnormal (hypersegmented) neutrophils and reduced overall cell counts (pancytopenia)

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Microbiome-derived lipopolysaccharide enriched in the perinuclear region of Alzheimer's disease brain