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At the same time, oxidative stress, which is caused by mitochondrial damage, activation of NADPH oxidase, and other environmental or treatment-related insults, promotes tumourigenesis through a cascade of events including: oxidative DNA adducts (8-oxo-dG), lipid peroxidation (4-HNE), protein oxidation, redox-regulated oncogene activation and mutagenesis, inhibition of the DNA repair machinery, and a vicious cycle of genomic instability accompanied by inflammatory signalling (178180)

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Draw bacteriostatic water: Use a sterile syringe to withdraw the desired amount

& Saliba, M

Such a TOA-effect is supportive for a compound mode-of-action related to early steps in the viral cycle, i.e., entry