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However, 24 patients did not complete the 90-day period due to various reasons: two patients started other intranasal medications, five voluntarily withdrew, nine were excluded by researchers for non-compliance, seven were lost to follow-up, and one patient died

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Real-world muscle gains may be modest

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Frontiers in Microbiology, 12 , Article 625952

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In a Phase 2 trial, weight loss with the CagriSema combination reached approximately 15.6%, compared with cagrilintide monotherapy at ~8.1% and semaglutide monotherapy at ~5.1%

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