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Study 1 (NCT 00123253) This study re-randomized 207 HIV-infected patients with lipodystrophy who completed a 2 mg dose of EGRIFTA (1 mg/vial formulation) treatment in the Main Phase to receive either EGRIFTA (N=154) or placebo (N=50) for an additional 26-week duration (3:1 randomization ratio)

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Pathophysiology of SARS-CoV-2 infection After entering the respiratory tract, SARS-CoV-2 attaches to nasal and bronchial epithelial cells and pneumocytes through its spike (S) protein, which binds to the angiotensin-converting enzyme (ACE2) receptor present on the surface of the cell membranes