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JAMA 331 , 3848 (2024)

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Image: porpeller | Getty Images About the Reviewer Howard E

Primary Research Applications Weight Management & Fat Loss Studies Clinical validation demonstrates remarkable 7% body weight reduction over 10 days in diet-induced obese mice without changes in food intake compared to controls

This process is similar to the mechanism of ferroptosis, where ROS generation is intensified, causing oxidative damage that can exacerbate adriamycin-induced cardiotoxicity