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For women, especially post-menopause or post-partum, the drop in estrogen and progesterone directly accelerates collagen loss (as quickly as 30% in the first five years after menopause!)

Left to their own devices, however, those activated skeletal stem cells regenerated fibrocartilage in the joint

Yes, lyophilized (freeze-dried) vials do best refrigerated at 3646F (28C), tolerate cool room temperature for short periods, and last longest frozen at -20C (-4F) or colder

Peptides are delicate molecules that require careful handling to preserve their biological activity, and the antimicrobial properties of bacteriostatic water ensure these peptides remain uncontaminated over time

Hence there were two main goals of this study