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- New improved formula helps increase the effectiveness of dark spot removal and skin brightening by 8 times

Unopened vials: Store at controlled room temperature (20-25 degrees C / 68-77 degrees F) Protected from light in original packaging Good until manufacturer-printed expiration date (typically 18-24 months from production) Do not freeze freezing can compromise the glass vial seal and alter preservative distribution After first puncture: Refrigerate at 2-8 degrees C (36-46 degrees F) 28-day use window from first needle puncture per Pfizer/Hospira prescribing information Swab the rubber stopper with 70% isopropyl alcohol before every puncture Label the vial with the first-puncture date Discard after 28 days regardless of remaining volume or visual appearance What shortens the 28-day window: Room-temperature storage after puncture (can reduce effective window to 7-10 days) Excessive puncture count (30+ punctures accelerate preservative depletion) Poor aseptic technique (skipping alcohol swabs introduces surface contamination) Temperature cycling (moving between fridge and room temp repeatedly) For a deep dive on shelf life, degradation signs, and the science behind the 28-day rule, see How Long Does Bac Water Last After Opening

2025;137(1):e70067

Tissue-Regeneration Research: BPC-157 is examined for its influence on angiogenesis and tissue-remodeling processes

Acknowledgements The researchers extend their appreciation to Postgraduate Studies & Research Sector, Assiut University for funding this work as a research number: AUN2025F