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Huo YX, et al

Metabolic changes in tamoxifen-resistant MCF-7 cell lines were manifested with the increase of glutathione, xanthine, and other metabolites involved in antioxidant pathways along with their dysfunctional genes' expression

No confirmed health risks due to unmetabolized folic acid have yet been found, but undiscovered risks may still exist

Besides the canonical effects on cholesterol levels, statins show pleiotropic effects on various cellular activities, such as proliferation, cell adhesion and migration, immune regulation, and endothelial functions (Pedersen, 2010)