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Peroxides reduction Protein SS groups reduction and Protein/GSH adducts cleavage Glutaredoxin GSSG cholesterol synthesis cholesterol synthesis and GSSG Glutathionylation Glutathionylation: a regulatory role of glutathione in physiological processes, 2018 Direct and indirect regulatory roles in physiological processes include glutathionylation of: major transcriptional factors, eicosanoids, cytokines, nitric oxide (NO) Which is the information content of GSH molecule

The experimental design, fish exposure and tissue isolation are described in detail in Barboza et al

Pb also hampers the production of ATP, causes the oxidation of lipids, and leads to DNA damage, culminating in an accumulation of ROS (Pourrut et al., 2011

Disrupted copper homeostasis has been shown to induce oxidative stress in various models [3, 17, 18]